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Study reveals e-cigarette users experience vascular damage similar to that of smokers of combustible cigarettes


WASHINGTON DC: An eye-opening study for those who have switched their conventional cigarettes to e-cigarettes advocates that the use of e-cigarettes damages the arteries and blood vessel serve as just like smoking conventional cigarettes.

The new analysis was printed in the Journal of the American Heart Association, an open get entry to journal of the American Heart Association, and funded during the Tobacco Center of Regulatory Science of the American Heart Association, the leading voluntary well being organization dedicated to a world of longer, fitter lives.

According to the study author Jessica L. Fetterman, Ph.D., assistant professor of drugs at Boston University School of Medicine, Boston. "Many people believe e-cigarettes are safer than combustible cigarettes. In fact, most e-cigarette users say the primary reason they use e-cigarettes is that they think e-cigarettes pose less of a health risk. Meanwhile, the evidence from scientific studies is growing that e-cigarettes might not be a safer alternative to smoking traditional cigarettes when it comes to heart health. Our study adds to that evidence."

Fetterman and co-workers studied over 400 women and men, ages 21 to 45 years, who had no longer been identified with middle illness or middle illness chance factors. Study participants integrated 94 nonsmokers, 285 cigarette smokers, 36 e-cigarette users and 52 dual users who smoke combustible cigarettes and use e-cigarettes. Combustible cigarette smokers and dual users had been older than non-smokers and e-cigarette users, while e-cigarette users had been more likely to be more youthful, male and white. All e-cigarette users had been former smokers of conventional cigarettes.

"We studied measures of blood vessel function in e-cigarette and dual users who had been using e-cigarettes for at least three months. Most studies to date have looked at the impact of the acute use of e-cigarettes on blood vessel function measured right before and after use, whereas our study evaluated blood vessel function in chronic e-cigarette use among young, healthy adults," Fetterman said.

The researchers found that former smokers who switched to e-cigarettes and dual users had an augmentation index very similar to conventional cigarette users, which means that that their arteries had been simply as stiff.


"Stiffening of the arteries can cause damage to the small blood vessels, including capillaries, and puts additional stress on the heart, all of which can contribute to the development of heart disease," Fetterman said.


The researchers additionally found that the cells that line the blood vessels, called endothelial cells, gave the impression to be similarly as broken whether other people used e-cigarettes, combustible cigarettes or each.


"The endothelial cells from e-cigarette users or dual users produced less of the heart-protective compound nitric oxide, compared to non-tobacco users. Their cells also produced more reactive oxygen species, which cause damage to the parts of cells such as DNA and proteins," Fetterman said. "Our study results suggest there is no evidence that the use of e-cigarettes reduces cardiovascular injury, dysfunction or harm associated with the use of combustible tobacco products."


She famous longer-term research are needed to resolve if vascular injury from e-cigarettes on my own changes over time.


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